Therapeutics And Prevention of E. Coli

 

        E. coli can replicate rapidly, making timely intervention essential to prevent disease 

progression. Initial supportive care focuses on maintaining hydration and electrolyte balance. 

Antibiotics such as ciprofloxacin, rifaximin, bismuth subsalicylate, and azithromycin may be 

prescribed depending on the strain and resistance patterns (Hong et al., 2010). However, 

antimotility drugs, though useful for acute watery diarrhoea, can worsen symptoms in cases of 

bloody diarrhoea (Moss, 2010). For EHEC, avoiding antibiotics is recommended as they may 

increase the risk of HUS (Sevilla et al., 

2025). Hygiene is essential in 

preventing E. coli infections, and 

vaccine development is underway (Long 

et al., 2010). General preventive

strategies include proper hand hygiene 

and careful consideration of food sources 

to minimise exposure to contaminated sources.